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Biocceleration Releases GenCore 6,
A New Sequence Search Acceleration System

October 10, 2005 – Biocceleration Ltd. announced the release of GenCore 6, its next generation sequence search acceleration system. As the fourth generation of the market leading Bioccelerator product line, the GenCore 6 system builds on Biocceleration’s vast experience from dozens of installations around the world, and is the most comprehensive, production level system available today.

The main features of the GenCore 6 system are:

-     A robust software package that runs on standard, general purpose computing and network architectures (Intel Pentium-4 processor based systems or others), using Linux or other Unix operating systems.

-    Software based acceleration, using Biocceleration's highly optimized proprietary software implementation.

-    Up to 10-fold speed improvement relative to standard software implementations. More then 2 Billion Smith-Waterman Matrix cells calculations per second on a dual 3GHz P4 Linux machine. For detailed benchmarks see:

-    Support for a comprehensive set of search algorithms including Smith-Waterman (with affine scoring), ProfileSearch, ProfileScan, Translated Searches, Frame+, ProfileFrame+, HMMsearch, HMMscan, GeneWise

-    Seamless integration with a wide variety of DNA and protein database formats including FASTA, BLAST, GenBank, EMBL, SwissProt, GCG, NBRF, PIR, RAW, IG, PFAM (HMM)

-    Full user control over search parameters such as gap penalties, comparison tables, translation tables, scoring and normalization methods, and others.

-    Multi-query operation enables multiple sequences, or even a database subset, to be submitted as the search query set.

-    Multi-threaded operation enables full utilization of multiprocessor Unix/Linux machines.

-    Band, linear memory alignment algorithm for all search applications, produces fast, accurate alignment, even for very long sequences.

-    Support for multiple normalization methods enables customizing the software output for specific research projects.

With free download license for academic and research institutes, and reasonably priced license for commercial entities, Biocceleration enables existing Bioccelerator customers (BioXL/G, BioXL/P, BioXL/H), and new customers, easy upgrade to a new level of database search speed, performance, and flexibility.

For additional information, please visit Biocceleration’s products page at: http://www.biocceleration.com/Products.html
or contact us at info@biocceleration.com

Biocceleration Ltd. , a bioinformatics company, is the leading provider of systems and solutions for accelerating searches in protein and nucleic acids databases. Biocceleration provides software and hardware solutions that accelerate rigorous database search algorithms, like HMMsearch and Smith-Waterman by a factor of 10-1000 relative to general purpose servers. With install base of more then 50 biotech companies, pharmaceutical companies, and academic research institutes, Biocceleration offers a suite of hardware accelerators and software packages to support the industry needs for accelerated protein and DNA database searches.